Figure 1.
The HBP peptide from BMP4.
Notes: (A) Amino acid sequences of the heparin-binding sites of TGFβ1, FGF, and PDGF. The heparin-binding sites of angiogenic growth factors consist of positively charged amino acids, such as Arg, Lys, and His. (B) The coincidence of HBP with the heparin-binding consensus sequence (purple circles, basic amino acids; red diamonds, hydrophobic amino acids; blue ovals, turns). The three-dimensional structure shows the structural turn at proline.
