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. 2016 Sep 13;11:4643–4656. doi: 10.2147/IJN.S115044

Figure 1.

Figure 1

The HBP peptide from BMP4.

Notes: (A) Amino acid sequences of the heparin-binding sites of TGFβ1, FGF, and PDGF. The heparin-binding sites of angiogenic growth factors consist of positively charged amino acids, such as Arg, Lys, and His. (B) The coincidence of HBP with the heparin-binding consensus sequence (purple circles, basic amino acids; red diamonds, hydrophobic amino acids; blue ovals, turns). The three-dimensional structure shows the structural turn at proline.