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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Immunol. 2016 Aug 29;197(7):2748–2761. doi: 10.4049/jimmunol.1501926

Figure 2. Protective effect of homologous Ad5 or Ad5/3 regimens.

Figure 2

Effects of homologous prime-boost regimens based on Ad5 or Ad5/3, after experimental challenge with P. yoelii sporozoites. (A) Parasitemia presented as an area under the curve (AUC) of parasitemia vs time and (B) hemoglobin levels presented as the lowest recorded hemoglobin value expressed as a percentage of the baseline hemoglobin. Results are shown for groups of mice immunized with the specified regimens. Data are the summary of the results of two independent experiments (n=12 mice). Error bars show standard deviations. Immunization groups were compared to a control group receiving empty adenoviral vectors immunizations using one-way ANOVA and Bonferroni’s Post-test *p<0.05, *p<0.0001.