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. Author manuscript; available in PMC: 2017 Oct 1.
Published in final edited form as: J Immunol. 2016 Aug 29;197(7):2748–2761. doi: 10.4049/jimmunol.1501926

Figure 6. Protective effect of the prime-boost strategy including recombinant Ad5 or Ad5/3 vectors.

Figure 6

Effect of heterologous prime-boost regimens based on Ad5 (Left Panels) or Ad5/3 (Right Panels) on Parasitemia (A–B) expressed as an area under the curve of Parasitemia vs Time and hemoglobin levels (C–D) expressed as the lowest recorded hemoglobin presented as percentage of the baseline hemoglobin. 20 days after the final immunization mice were challenged with P. yoelii sporozoites. Data are the summary of the results of two independent experiments (n=12 mice). Error bars show standard deviations. Immunization groups were compared to a control group receiving empty adenoviral vectors immunizations using one-way ANOVA and Bonferroni’s Post-test *p<0.05, *p<0.001.