Table 4.
Comparison of the changes of the variables in AMI patients with or without depression before and after treatment with or without antidepressant
| Variables | AMI-N (n=225)
|
AMID-A (n=46)
|
||
|---|---|---|---|---|
| Before | After | Before | After | |
| HAMD-17 | 7.1±3.6 | 7.6±4.5 | 27.3±4.5** | 13.5±4.9*,*** |
| SDS | 38.7±7.9 | 38.4±7.8 | 57.3±4.6** | 43.7±5.5*,*** |
| LVEF (%) | 38.3±4.2 | 42.3±5.8* | 38.1±5.8 | 47.9±7.0*,** |
| HRV | ||||
| SDNN (ms) | 32±10 | 49±11* | 23±11** | 59±18*,*** |
| HF (ms2) | 379±136 | 489±153* | 253±110** | 587±183*,*** |
| LF (ms2) | 428±173 | 576±130* | 350±177** | 643±249*,*** |
| LF/HF (%) | 69±36 | 104±87* | 44±46** | 304±94*,*** |
| EPI (pg/mL) | 89.8±13.2 | 54.2±8.9* | 114.8±19.7** | 46.1±5.9*,*** |
| NE (pg/mL) | 838.2±154.7 | 692.5±108.9* | 983.1±281.9** | 510.6±176.3*,*** |
| SBP (mmHg) | 134±14.8 | 127±10.3 | 138±11.9 | 117±8.3* |
| DBP (mmHg) | 81±7.4 | 75±6.7 | 85±7.2 | 72±6.5 |
Notes: Data was expressed as mean ± SD.
P<0.01 compared with before treatment within groups.
P<0.01 compared with before treatments of AMI.
P<0.01 compared with after treatments of AMI.
Abbreviations: A, antidepressant; AMI, acute myocardial infarction; AMID, acute myocardial infarction with depression; DBP, Diastolic blood pressure; EPI, epinephrine; HAMD-17, 17-item Hamilton Depression Scale for Depression; HF, high frequency; HRV, heart rate variability; LF, low frequency; LF/HF, LF-to-HF ratio; LVEF, left ventricular ejection fraction; N, non-antidepressant; NE, norepinephrine; SBP, systolic blood pressure; SD, standard deviation; SDS, Self-rating Depression Scale; SDNN, standard deviation of all normal beats.