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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Cell Physiol. 2016 Jun 21;232(1):216–224. doi: 10.1002/jcp.25413

Figure 5. High glucose differentially affects cell survival depending on the ΔΨm, and blocks APC.

Figure 5

(A) Oxidative stress-induced cell death was significantly greater in high glucose (↑Gluc.) than in control (Ctrl.). Addition of DNP reversed this effect to cytoprotection, which was also observed in hyperosmotic group (↑Osm.). Data are means ± SD. *P < 0.05 vs. Ctrl; #P < 0.05 vs. ↑Gluc. (B) Compared to control, APC attenuated cell death, but failed to do so in ↑Gluc. ↑Osm. did not abolish APC-induced cytoprotection. *P < 0.05 vs. Ctrl; #P < 0.05 vs. APC + ↑Gluc.