Table 4.
Genetic characterization of H.pylori strains isolated from gastritis patients
| Patien t |
Biopsy location |
Intergenic region* |
cagA | Empty site** | hspA | vacA s/m | Culture conditions |
|---|---|---|---|---|---|---|---|
| 1 | A/C | − | + | + | s1/m2 | Anaerobic | |
| 3 | A/C | − | + | + | s1/m1/m2 | Micro/Ana | |
| 4 | A | − | + | + | s1/m1 | Anaerobic | |
| 5 | A/C | − | + | + | m1/m2 | Anaerobic | |
| 7 | A/C | − | + | + | s1/m2 | Anaerobic | |
| 8 | C | − | − | − | + | s1/m2 | Micro/Ana |
| 17 | A | − | − | + | + | s1/m2 | Anaerobic |
| 19 | C | − | + | + | s1/m1/m2 | Micro/Ana | |
| 21 | A | − | − | − | + | s1/m2 | Anaerobic |
| 23 | A | − | + | + | s1/m2 | Micro/Ana | |
| 24 | A/C | − | + | + | s1/m2 | Micro/Ana | |
| 25 | A | − | − | + | + | s1/m2 | Anaerobic |
| 26 | A/C | − | + | + | s1/m1 | Anaerobic | |
| 27 | A | − | + | + | s1/m1 | Anaerobic |
A= antrum
C= corpus
s= signal sequence
m=middle region
Micro=micro-aerobic conditions
Ana=anaerobic conditions
*
Negative for the 180bp insert
**
Empty-site PCR was performed only on cagA negative strains in order to determine presence or absence of the cag pathogenicity island. The presence of a band in the empty site PCR represents the lack of Pathogenicity Island.