Table 3.

Associations between brain responses to evoked pain (BOLD), MOR availability (MOR BP), and McGill affective/ sensory pain ratios. Bolded regions were significantly associated with clinical pain.

Brain region	MNI co-ordinates (X Y Z)	Affective/Sensory Pain Ratio
		r	P
Whole Brain
MFG (BOLD)	−12, 2, 62	−.518	.027
MOR BP		−.629	.005
PCC (BOLD)	−8, −44, 40	−.593	.010
MOR BP		−.497	.036
pgACC/MFG (BOLD)	−16, 40, 38	−.581	.012
MOR BP		−.571	.013
Precentral (BOLD)	32, −4, 34	−.436	.070
MOR BP		−.507	.032
DLPFC (BOLD)	−42, 8, 28	−.331	.179
MOR BP		−.246	.324
MTG (BOLD)	−58, −58, 4	−.408	.093
MOR BP		−.410	.091
sgACC (BOLD)	8, 38, −2	−.754	<.001
MOR BP		−.545	.019
NAc (BOLD)	−18, 6, −12	−.425	.079
MOR BP		−.301	.224
Cerebellum (BOLD)	28, −58, −40	−.294	.236
MOR BP		−.318	.198
ROI
ACC (BOLD)	−12, 38, 28	−.378	.122
MOR BP		−.552	.018
NAc (BOLD)	−18, 6, −12	−.425	.079
MOR BP		−.301	.224

MFG=medial frontal gyrus, BOLD = blood oxygen level-dependent, MOR= μ opioid receptor, BP= binding potential, ACC= anterior cingulate cortex, PCC = posterior cingulate cortex, pg = perigenual, d= dorsal, DLPFC = dorsolateral prefrontal cortex, MTG = middle temporal gyrus, sg = subgenual, ROI = region of interest, NAc= nucleus accumbens