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. Author manuscript; available in PMC: 2017 Sep 22.
Published in final edited form as: Vaccine. 2016 Aug 28;34(41):4969–4978. doi: 10.1016/j.vaccine.2016.08.041

Fig. 6.

Fig. 6

Immediate pre-exposure prophylaxis with rLVS ΔcapB/bfr-iglABC but not LVS induces strong innate immunity. Mice were immunized with PBS (Sham), 102 of LVS, or 1 ×106 or 5 × 107 of rLVS ΔcapB/bfr-iglABC (bfr-iglABC) as indicated and euthanized at day 2 post immunization. Their lung lysates (A – C) and sera (D) were assayed for cytokine/chemokine production by a mouse 32-Plex kit. Shown are means ± SE (n = 3 mice) for each cytokine/chemokine. *, P<0.05; **, P < 0.01; ***, P< 0.001; ****, P< 0.0001 by Two-Way ANOVA with multiple comparisons (Prism 6.04).