Table 4.
Summary of predictors of muscle strength and physical functioning at 3 months after hospital discharge
| Variable n = 50a | 6-Minute walk test | Grip | Triceps | Biceps | Hamstrings | Quadriceps | Ankle dorsiflexors |
|---|---|---|---|---|---|---|---|
| ICU LOS, days | −0.003 (0.041) | −0.002 (0.85) | −0.010 (0.305) | −0.005 (0.537) | −0.001 (0.806) | 0.000 (0.922) | −0.001 (0.685) |
| Hospital LOS, days | −0.003 (0.079) | −0.001 (0.965) | 0.002 (0.727) | 0.003 (0.498) | 0.000 (0.969) | 0.003 (0.274) | 0.001 (0.755) |
| Mechanical ventilation, days | −0.004 (0.045) | −0.001 (0.905) | −0.009 (0.378) | −0.004 (0.610) | −0.001 (0.899) | 0.001 (0.809) | −0.001 (0.742) |
| Presence of sepsis | −0.168 (0.029) | −0.389 (0.009) | −0.328 (0.045) | −0.315 (0.033) | −0.328 (0.016) | −0.134 (0.262) | −0.197 (0.049) |
| APACHE II score | −0.003 (0.642) | −0.002 (0.868) | −0.008 (0.515) | 0.003 (0.802) | 0.003 (0.755) | 0.011 (0.212) | 0.006 (0.397) |
| SOFA score | 0.011 (0.257) | 0.022 (0.229) | 0.021 (0.325) | 0.027 (0.167) | 0.020 (0.219) | 0.019 (0.174) | 0.017 (0.154) |
| Functional Comorbidity Index | −0.019 (0.593) | −0.070 (0.247) | −0.111 (0.114) | −0.050 (0.437) | −0.000 (0.998) | 0.013 (0.803) | −0.044 (0.274) |
| Any corticosteroid useb | −0.215 (0.019) | −0.304 (0.092) | −0.382 (0.062) | −0.359 (0.052) | −0.320 (0.047) | −0.222 (0.137) | −0.221 (0.058) |
ICU intensive care unit, LOS length of stay, APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, 6MWT 6-min walk test
aβ-Coefficients (p value) modeled as univariate regression analyses. 6MWT and muscle strength modeled as percent predicted. β-Coefficients represent the percent change in the physical functioning variable per unit change in exposure variable
bAlso analyzed using cumulative ICU and average daily corticosteroid dose with no significance found