Figure 1.

AnkA binding sites unique to, or in common with those in 3 human neutrophil DNA genome preparations. The total number of AnkA binding sites for each of the 3 neutrophil DNA preparations after DNA interaction, immunoprecipitation, and sequencing is shown. The Venn diagram demonstrates the core shared among each genome, those shared among 2 genomes, and those uniquely identified in each. For each sequencing reaction, peak calls were identified by FindPeaks and the intersection of these was generated to identify unique or shared binding sites. For ChIP regions of variable length reads, the midpoint was defined (average of the start and end points) and compared to the next closest neighbor assigned by start point. Those that differed by < 100 bp were defined as the same AnkA binding region.