Table 1. Pearson correlation coefficients for the co-evolution of the UPF0261 and TBST proteins using the RefSeq protein dataset and Mirrortree method.

Lineage	RefSeq proteins			Mirrortree
	Genomes	r	P	Genomes	r	P
Common	416	0.7192	<0.0001	159	0.886	<0.0001
Bacteria	333	0.7735	<0.0001	136	0.906	<0.0001
Archaea	22	0.7185	<0.0001	3	0.990	<0.05
Fungi	61	0.8067	<0.0001	19	0.867	<0.0001