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. 2016 Sep 20;6:33679. doi: 10.1038/srep33679

Figure 6. mBPIN-GVNPs decreased inflammatory cytokine levels in the blood during later stages of inflammation.

Figure 6

Cohorts of 5 mice were either injected with PBS (white bars) or first pre-treated with WT-GVNPs (100 μl of 1 mg/ml), then challenged with LPS and D-galactosamine (black bars) or first pre-treated with mBPIN-GVNPs (100 μl of 1 mg/ml) via foot pad injection 1 h before treatment and then challenged with a combination of LPS and D-galactosamine (checkered bars). Data shown is from blood collected at 2 and 6 hours post-challenge. Serum cytokine levels were measured using Luminex analysis. (a) TNF-α levels; (b) IL-6 levels; (c) MIP-2 levels; and (d) KC levels. Key: ***p < 0.001, **P < 0.01, *p < 0.05, ns = not significant.