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. 2016 Sep 20;6:33670. doi: 10.1038/srep33670

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Copyright © 2016, The Author(s)

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FLE-Am genome is on the right and F. tularensis tularensis SCHU-S4 genome is on the left. The outer two rings show protein-coding genes (blue in FLE-Am and green in F. tularensis). Rings 3 and 4 contain virulence genes (intact genes in orange and pseudogenes in black). Amino acid biosynthesis genes (green) are in ring 5. Cofactor synthesis and transport genes (purple) are in ring 6, and tRNAs (black) and rRNAs (red) are in ring 7. Sequencing read coverage for FLE-Am is shown in the innermost black semi-circle. Notice that the coverage for the rRNA operon is double that of the rest of the genome. The table in the center highlights the inactivation and loss of virulence genes in FLE-Am.