Figure 3. ApoE^−/− mice infected with P. berghei ANKA maintain BBB integrity.

(A) Representative pictures of brains from uninfected and infected WT and ApoE^−/− mice injected with Evans blue. (B) Quantification of Evans blue in the brain parenchyma. n = 6 for uninfected and infected WT mice and n = 8 for uninfected and infected ApoE^−/− mice; P = 0.0035. Infected WT mice analyzed on day 9 post-infection and infected ApoE^−/− mice analyzed on day 16 post-infection (based on their median survival times). **P ≤ 0.01.