Table 3.

Pharmacy and Medical Costs (Model Inputs)

Parameter	ATO + ATRA (first-line)1	ATRA + IDA (first-line)1	ATRA + AraC + Additional Chemotherapy (first-line)2	ATO Regimen (second-line)3
Total pharmacy4	$61,797	$13,146	$38,008	$33,241
Induction phase: medical5	$20,503	$20,503	$20,503	$20,503
Consolidation phase: medical5	$778	$778	$778	$778
Maintenance phase: medical5	N/A	$40	$40	N/A
Off-treatment medical monitoring6	$177	$177	$177	$177
Disease event: medical7	N/A	N/A	N/A	$483
Autologous stem-cell transplant8	N/A	N/A	N/A	$4,717

¹Source = Lo-Coco, 2013¹⁷;

²Source = Powell, 2010²⁰;

³Source = Yanada, 2013²²;

⁴Pharmacy costs were estimated using wholesale acquisition costs (WAC);

⁵Medical costs were estimated from standard US costing sources using the average diagnosis-related group (DRG) cost for all inpatient services plus Current Procedural Terminology (CPT) codes by treatment phase;

⁶Patients\assumed to have an oncologist office visit every 3 months;

⁷One-time costs associated with a disease event post second-line treatment calculated in consultation with a clinical expert;

⁸Patients who received a autologous stem-cell transplant post second-line treatment incurred costs for procedures assumed to be on an outpatient basis.

Note: It was assumed that patients are hospitalized after a disease event post first-line treatment and any costs would be included in the DRG cost for second-line treatment.