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Mice infected with the omamA mutant have reduced histopathology compared to WT infected mice. A. A single lung lobe from was fixed and H&E stained for histology. Shown are representative images captured under 2X and 20X magnification from 20 and 127 days post infection comparing WT (MBTB178), omamA::tn (MBTB319), and omamA::tn + omamA (MBTB320). B. Average histological activity index (HAI) scores were determined by an experienced blinded reviewer.
