OmamA is an integral membrane protein that is important to Mce transporter stability and function. OmamA (pink) and other Mam proteins (red) are embedded in the inner membrane by an N-terminal transmembrane domain with the majority of the protein being localized on the cell wall side of the membrane. Mce permease proteins (YrbE), shown in green, are multi-membrane spanning proteins localized to the inner membrane. Some Mce proteins contain predicted TM domains; however, localization from this and other studies (Klepp et al., 2012) suggests that Mce proteins are located within the cell wall (shown in purple). MceG, shown in yellow, is the cytoplasmic Mkl family ATPase predicted to be responsible for ATP-hydrolysis that powers the transport of substrates, shown in light pink, through the complex.