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. 2016 Sep 20;15:481. doi: 10.1186/s12936-016-1533-x

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — The slow acting characteristics of dihydronitidine. a Dose–response curves for P. falciparum (3D7) in 48 h in vitro drug assays showing unusual response to dihydronitidine. b Response of parasites to increasing time of dihydronitidine exposure. Maximum efficacy is reached at 72 h, with no improvement with longer exposures