Table 2.
Comparison of tuberculosis treatment outcome between patients receiving and not receiving directly observed treatment, separated by census tract of residence: slum (aglomerados subnormais - AGSN) and non-slum (non-AGSN), Rio de Janeiro, Brazil, 2010
| AGSN | Non-AGSN | P-value† | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| DOT (%) | RR§ | 95 % CI | DOT (%) | RR§ | 95 % CI | ||||||
| Total | Yes | No | Total | Yes | No | ||||||
| Missing outcome | 174 (10.2) | 39 (6.1) | 135 (12.7) | 0.56 | 0.42-0.74 | 462 (10.2) | 98 (7.9) | 364 (11.0) | 0.77 | 0.64-0.92 | 0.06 |
| Cure | 963 (56.7) | 430 (67.4) | 533 (50.1) | 1.66 | 1.45-1.91 | 2622 (57.8) | 758 (61.4) | 1864 (56.5) | 1.15 | 1.04-1.27 | <0.01 |
| Abandonment | 325 (19.1) | 118 (18.5) | 207 (19.5) | 0.97 | 0.83-1.14 | 746 (16.5) | 265 (21.5) | 481 (14.6) | 1.37 | 1.23-1.53 | <0.01 |
| Death TB | 68 (4.0) | 8 (1.3) | 60 (5.6) | 0.20 | 0.08-0.46 | 199 (4.4) | 28 (2.3) | 171 (5.2) | 0.54 | 0.38-0.76 | 0.03 |
| Death other | 32 (1.9) | 9 (1.4) | 23 (2.2) | 0.68 | 0.37-1.24 | 128 (2.8) | 24 (1.9) | 104 (3.2) | 0.65 | 0.45-0.95 | 0.92 |
| Transfer out | 140 (8.2) | 34 (5.3) | 106 (10.0) | 0.57 | 0.41-0.78 | 378 (8.3) | 61 (4.9) | 317 (9.6) | 0.60 | 0.47-0.75 | 0.82 |
*There were 88 (4.4 %) cases in AGSN and 219 (4.4 %) outside of AGSN where the case’s DOT status was unknown
§Relative risk (RR) estimating crude risk of outcome in patients undergoing DOT compared to patients not undergoing DOT in slum versus non-slum neighborhood
† P-values assessing for effect measure modification of AGSN census tracts on the relationship between DOT and respective outcome with the Mantel-Haenszel chi-square test