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. 2016 Jan 19;10(8):1815–1822. doi: 10.1038/ismej.2015.247

Table 1. Examples of key microbial hyperparasites and their effect on pathogens.

Hyperparasite Pathogen(s) Hosts Key effects References
Cryptophonectria hypovirus-1 (CHV1) Cryphonectria parasitica Chestnut trees (genus Castanea) Reduces pathogen growth rate and virulence to host. Alters genetic structure of C. parasitica populations. Allows tree host populations to recover to near disease-free demography Hillman and Suzuki (2004); Milgroom and Cortesi (2004) Springer et al. (2013) Davelos and Jarosz (2004)
Ampelomyces quisqalis Podosphaera spp. Erysiphe spp. Oidium spp. Arthrocladiella mougeotii Golovinomyces spp. Sphaerotheca fuliginea Numerous plant species including: Plantago spp. Cucumber Grape Apple Strawberry Reduced pathogen growth Reduced pathogen overwintering success Reduced pathogen sporulation Rescues host plant chloroplast from deterioration Verhaar et al. (1996) Tollenaere et al. (2014) Falk et al. (1995) Shishkoff and McGrath (2002) Angeli, et al. (2012) Abo-Foul et al. (1996) Romero et al. (2003)
Unknown fungal hyperparsites Orphycordyceps camponoti-rufipedis Ant: Camponotus rufipes Castrates immature fruiting body and reduces viability of spores. Limits transmission effeciency of the pathogen. Andersen et al. (2012)
APSE phage Hamiltonella defensa Aphid: Acyrthosiphon pisum Reduces bacterial abundance in aphid host. Phage loss associated with fitness reduction in H. defensa infected aphids. Phage presence linked to protective property of H. defensa against aphid's natural enemies. Weldon et al. (2013)
JSF4 bacteriophage Vibrio cholera Human Phage lysis associated with self-limiting bacterial epidemic. Faruque et al. (2005)
LESϕ prophage Pseudomonas aeruginosa Human Phage lysis associated with bacterial population size regulation. James et al. (2015)