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. 2015 Nov 27;10(6):1456–1470. doi: 10.1038/ismej.2015.209

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Copyright © 2015 International Society for Microbial Ecology

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/

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The synbiotic approach improves intestinal immune and barrier biomarkers in leukaemic mice. (a) mRNA expression of markers involved in Paneth cell differentiation and antimicrobial proteins. (b) mRNA expression of markers involved in gut permeability. (c) mRNA expression of immune markers related to inflammation, innate immunity (CD11b) and macrophages. (d) mRNA expression of immune markers related to lymphocytes (CD3γ) Th1 (Tbet), Th17 (IL-17A) and Treg (Foxp3, IL-10, Ebi3) cells. N=7–8, *P<0.05 vs control, ^#P<0.05 vs BaF.