Figure 4.

Deterministic and stochastic dynamics of TOL network components in different growth phases. Differences in Pu promoter activation, Pu mRNA variability and GFP induction in exponential (a, b) and stationary (c, d) phases. (a) Time evolution of active XylR (top panel), active Pu promoter (intermediate panel) and Pu mRNA (low panel). Black line is the stochastic simulation and coloured lines the deterministic results. (b) Seven stochastic trajectories mimicking GFP induction in different cells during the time course of experiments. (c, d) The same variables and GFP trajectories in stationary phase conditions.