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. 2016 Sep 20;7:1477. doi: 10.3389/fmicb.2016.01477

FIGURE 4.

FIGURE 4

(A) Electron micrograph showing two chondrocyte with lacunae. Vesicular nuclei (N), and cytoplasm with few organelles are evident. Chondrocytes are surrounded by a matrix full of collagen fibrils. (Control group, TEM, ×8000). (B) Electron micrograph of the arthritic group showing one chondrocyte with large vacuoles in the cytoplasm and another chondrocyte that appears shrunken with irregular contours, scanty cytoplasm, and a dark, irregular nucleus. (Arthritis group, TEM, ×8000). (C) Electron micrograph showing two chondrocytes within lacunae with vesicular nuclei and normal cytoplasm. (Group treated with methanolic extract of the fungus, TEM, ×8000). (D) Electron micrograph of the group treated with an ethyl acetate extract of the fungus, showing one shrunken chondrocyte with dark nucleus (↑), and empty lacuna (∗). (Methanolic extract of the fungus group, TEM, ×8000). (E) Electron micrograph of the group treated with a methanolic extract of the fungus, showing apoptotic bodies (↑) in a shrunken chondrocyte with dark nucleus (↑↑). (Methanolic extract of the fungus group, TEM, ×15000).