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. 2016 Sep 20;6:33856. doi: 10.1038/srep33856

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Copyright © 2016, The Author(s)

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(A) There were no significant differences in the mRNA levels of SP-A, SP-B, SP-C, SP-D, T1-α, CC-10 and tropoelastin between the Loxl3^−/− and Loxl3^+/+ lungs. The Loxl3^−/− lungs exhibited a significant increase in the TGFβ1 mRNA levels. n = 3 in each group. *P < 0.05. (B) Western blots for TGFβ1 and β-actin in E18.5 Loxl3^+/+ and Loxl3^−/− lungs were analysed. The increased levels of the TGFβ1 protein were detected in the Loxl3^−/− lungs. n = 4 in each group. P = 0.069.