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Batf3-dependent accumulation of CD103+ DCs mediates tissue-specific production of IL-12 during systemic, but not oropharyngeal candidiasis. IL-12 levels were measured in Batf3+/+ and Batf3−/− mice in the kidney at day 4 after intravenous C. albicans infection (A) or in the tongue at day 1 after sublingual C. albicans infection (B). Data were analyzed using unpaired t-test (A) or Mann-Whitney U test (B). Data are combined from 2 independent experiments with a total n of 6–8 mice/group.
