Table 2.
Baseline Demographic, Clinical, and Outcome Factors of Study Participants.
| Total With CVT (n = 108) | True Positive CVT (n = 84) | False Negatives CVT (n = 24) | P Value | |
|---|---|---|---|---|
| Demographic factors | ||||
| Mean age (SD) | 48.5 (20.0) | 45.8 (18.64) | 58.13 (21.8) | 0.007 |
| Sex, women (%) | 56 (51.9%) | 40 (47.6%) | 16 (66.7%) | 0.08 |
| Pregnant or postpartum (%) | 5 (4.6%) | 1 (1.2%) | 4 (16.7%) | 0.001 |
| Medical center | ||||
| Hospital of the University of Pennsylvania (%) | 80 (74.1%) | 63 (75.0%) | 17 (70.8%) | 0.79 |
| CVT type | ||||
| Isolated cortical vein (%) | 11 (10.2%) | 1 (1.2%) | 10 (41.7%) | P < .001 |
| Single dural sinus (%) | 47 (43.5%) | 43 (51.2%) | 4 (16.7%) | 0.003 |
| Multiple dural sinuses (%) | 48 (44.4%) | 40 (47.6%) | 8 (33.3%) | 0.25 |
| Isolated deep cerebral vein (%) | 2 (1.9%) | 0 | 2 (8.3%) | 0.05 |
| Imaging modality | ||||
| MRI (%) | 80 (74.1%) | 61 (72.6%) | 19 (79.2%) | 0.61 |
| MRV (%) | 44 (40.7%) | 31 (36.9%) | 13 (54.2%) | 0.16 |
| CTV (%) | 32 (29.6%) | 24 (28.6%) | 8 (33.3%) | 0.80 |
| Either CTV or MRV (%) | 71 (65.7%) | 54 (64.3%) | 17 (70.8%) | 0.63 |
| Hospital outcome | ||||
| In-hospital death (%) | 8 (6.5%) | 6 (7.1%) | 2 (8.3%) | 0.57 |
| Median LOS, days [IQR] | 6.5 [3-15] | 7 [3-16] | 6 [3.3-10.8] | 0.82 |
Abbreviations: CTV, computed tomography venography; CVT, cerebral venous thrombosis; IQR, interquartile range; LOS, length of stay; MRI, magnetic resonance imaging; MRV, magnetic resonance venography; SD, standard deviation.