Table 1.
Patient Characteristics (Safety Population, N = 32)
| Demographic or Baseline Characteristic | StaccatoPlacebo (N = 8) | StaccatoLoxapine 15 mg (N = 8) | StaccatoLoxapine 20 mg (N = 8) | StaccatoLoxapine 30 mg (N = 8) | Overall Study Population (N = 32) |
|---|---|---|---|---|---|
| Sex, n (%): | |||||
| Female | 3 (37.5%) | 2 (25.0%) | 3 (37.5%) | 2 (25.0%) | 10 (31.3%) |
| Male | 5 (62.5%)a | 6 (75.0%) | 5 (62.5%) | 6 (75.0%) | 22 (68.8%) |
| Age (years) | |||||
| Mean (SD) | 40.4 (10.8) | 42.5 (7.7) | 44.3 (8.1) | 50.9 (11.3) | 44.5 (10.0) |
| Median | 40.5 | 43.5 | 45.0 | 53.0 | 44.5 |
| Min, max | 24, 56 | 27, 52 | 33, 56 | 34, 65 | 24, 65 |
| Height (cm) | |||||
| Mean (SD) | 169 (5.6) | 164 (15.2) | 173 (6.7) | 175 (9.0) | 170 (10.2) |
| Median | 169 | 165 | 173 | 175 | 170 |
| Min, max | 160, 175 | 137, 183 | 165, 183 | 163, 185 | 137, 185 |
| Weight (kg) | |||||
| Mean (SD) | 79.0 (12.8) | 91.2 (13.8) | 82.6 (13.2) | 89.4 (17.2) | 85.6 (14.6) |
| Median | 74.6 | 95.1 | 80.3 | 92.9 | 86.8 |
| Min, max | 63.5, 95.5 | 63.0, 106 | 62.5, 104 | 61.4, 111 | 61.4, 111 |
| Race, n (%) | |||||
| Caucasian | 0 | 0 | 1 (12.5%) | 0 | 1 (3.1%) |
| Black | 8 (100%) | 7 (87.5%) | 7 (87.5%) | 8 (100%) | 30 (93.8%) |
| Hispanic | 0 | 0 | 0 | 0 | 0 |
| Asian | 0 | 0 | 0 | 0 | 0 |
| Native American | 0 | 1 (12.5%) | 0 | 0 | 1 (3.1%) |
| Smoking history, n (%) | |||||
| Current smoker | 7 (87.5%) | 7 (87.5%) | 7 (87.5%) | 7 (87.5%) | 28 (87.5%) |