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. 2016 Apr 5;7(17):23072–23087. doi: 10.18632/oncotarget.8604

Figure 2. Immunohistochemical staining for AGEs and RAGE in pancreatic islets of db/db diabetic mice.

Figure 2

Immunohistochemical staining for AGEs A. and RAGE B. in pancreatic sections from db/db and db/m+ mice were shown. Original magnification, ×400, scale bar: 100 μm; x1000, scale bar: 50 μm. The arrows showed that indicated areas have enlarged scales. C. Serum AGEs detection was determined by ELISA. D. The protein expression of AGE-BSA in islets of db/db and db/m+ mice determined by Western blotting. Data are presented as means ± SEM (n = 10). *P < 0.05, versus db/m+ mice.