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. 2016 Mar 15;7(17):23197–23211. doi: 10.18632/oncotarget.8099

Figure 6. Effects of STARD13- and its ceRNAs-3’UTRs on metastasis and EMT of breast cancer in a xenograft model.

Figure 6

a. Whole animal imaging analysis of mice (n = 5 per group) injected with MDA-MB-231 cells stably overexpressing STARD13-, CDH5-, HOXD1-, and HOXD10-3’UTRs. Ventral views were shown for all five groups on day 14 and day 21. b. and c. HE-staining of lungs b. and livers c. isolated from mice that received tail vein injection of MDA-MB-231 cells stably overexpressing STARD13-, CDH5-, HOXD1-, and HOXD10-3’UTRs (n = 5 per group). Magnification ×200. Scale bars 50 μm. d. Immunohistochemical staining of E-cadherin (upper panel) and vimentin (lower pannel) in tumors subcutaneously injected with MDA-MB-231 cells stably transfected with STARD13-, CDH5-, HOXD1-, and HOXD10-3’UTRs or an empty vector. The brown signal corresponded to E-cadherin or vimentin. Magnification ×400. Scale bars 20 μm.