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. 2016 Mar 14;7(17):23512–23520. doi: 10.18632/oncotarget.8049

Figure 2. NNK exposure lead to EMT and enhanced the migration and invasion in HT29 cells.

Figure 2

A. LT-NNK exposure induced the EMT phenomenon with morphological transformation and alterations of cellular configuration in HT29 cells. B. LT-NNK exposure enhanced the abilities of migration and invasion. C. LT-NNK exposure altered EMT representative markers with decreased the expression of E-cadherin, increased the expression of vimentin, and significantly upregulated Snail signaling pathway in HT29 cells.