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. 2016 Mar 14;7(17):23512–23520. doi: 10.18632/oncotarget.8049

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Copyright: © 2016 Lee et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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A. Knockdown of Snail altered the expression of apoptotic-related proteins and reverses the expression of RKIP. B. Knockdown of Snail decreased the expression of MDR1 and ABCG2. C. Knockdown of Snail increased the expression of E-cadherin, decreased the expression of vimentin, indicating a reversal of EMT phenomenon. D. Knockdown of Snail suppressed the expression of CSC properties with decreasing the expression of Nanog, OCT4. E. Knockdown of Snail declined the ability of sphere formation.