Table 1. Summary of functional alterations of HCC cells transfected with GP73 m109, m144, and m398*.
Cell functions | GP73 m109 | GP73 m144 | GP73 m398 | |||
---|---|---|---|---|---|---|
Control groups | Mock | GP73 wt | Mock | GP73 wt | Mock | GP73 wt |
Cell proliferation | – | – | – | – | – | – |
Cell motility | + | + | + + | + + | + | + |
Cell invasion ability | + | + | + + | + + | + | – |
Cell adhesion ability | – | + | + | + | – | – |
“–” not affected,“+” affected, “++” affected in a large scale.
Compared with the Mock group, the cell motility and invasion ability of GP73 wt group were “+”.