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. 2016 Mar 14;7(17):23552–23568. doi: 10.18632/oncotarget.8083

Figure 4. KLF8 promotes CXCR4-dependent TEM towards CXCL12.

Figure 4

(A) Illustration of the procedure for the TEM assay. (B) Overexpression of KLF8 is sufficient to promote CXCR4-dependent TEM of 10A-iK8 cells towards CXCL12. (C) Knockdown of KLF8 inhibits CXCR4-dependent TEM of 231-K8ikd cells towards CXCL12. (D) Overexpression of CXCR4 but not the dN20 mutant prevents TEM of 231-K8ikd cells towards CXCL12 from inhibition by knockdown of KLF8.