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. 2016 Mar 16;7(17):23757–23771. doi: 10.18632/oncotarget.8121

Figure 7. Relevance of E2F8-induced cyclin E1 and cyclin E2 activation in human cancers.

Figure 7

(A) Western blotting assay showing that the protein expression of E2F8, cyclin E1, cyclin E2, p-Rb and total Rb in 10 breast cancer samples. α-Tubulin was used as the loading controls. (B) Correlation analysis of E2F8 and cyclin E1, cyclin E2 and p-Rb expression, respectively. The expression levels of E2F8, Cyclin E1 and Cyclin E2 were determined by densitometry. The ratio of first sample (E2F8/α-tubulin, Cyclin E1/α-tubulin, Cyclin E2/α-tubulin) was considered as 1.0. r, Pearson correlation coefficient.