Figure 6. PIM1 overexpression causes reduced sensitivity to chemoterapeutic drugs.
HCT116 cells transduced with PIM1-expressing lentivirus, were treated with Doxorubicin, Cisplatin, Actinomycin D or Nocodazole. After 48 h treatment, cell viability was assessed by MTT assays. Quantification of cell viability from three independent experiments is reported as a column plot of the mean ±s.e.m. of the values normalized by control. *, P<0.05.