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. 2016 Mar 19;7(17):23897–23908. doi: 10.18632/oncotarget.8192

Figure 3. Network analysis of coding and long non-coding gene expression in CRC.

Figure 3

(A) Relationships between network modules and traits. Upper panel, dendrograms produced by average linkage hierarchical clustering of genes on the basis of topological overlap. Modules of co-expressed genes were assigned colors as indicated by the horizontal bar beneath each dendrogram. Modules from different networks with significant overlap (corrected hypergeometric P < 0.05) were assigned the same color. Lower leaves indicate greater similarity of transcript expression profiles within that module. Lower panel (three correlation bands), NC, PC and MC bands show correlations (cor.) to the corresponding modules. Positive (red) and negative (blue). (B–C) Pie charts indicating the abundance of lncRNAs within green and blue modules. Module members are defined as all transcripts that were positively correlated with the module eigengene. (D) The co-expression network of green module. (E) KEGG pathway enrichment annotations of green module. (F) The co-expression network of blue module. (G) KEGG pathway enrichment annotations of blue module.