Table 2. Combination index (CI) for Iso-3 plus TRAIL treatments, in U-937 and RAJI cells.
Cell Line | Concentration Iso-3 (μM) |
Concentration TRAIL (ng/ml) |
CI |
---|---|---|---|
U-937 | 5 | 1 | 0.77 |
15 | 2.5 | 0.43 | |
15 | 5 | 0.21 | |
RAJI | 5 | 100 | 0.36 |
15 | 50 | 0.22 | |
15 | 100 | 0.21 |
Cells were pre-treated with Iso-3 for 24 h before addition of TRAIL for an additional 24 h. CI is calculated from mean values of at least three independent trypan blue exclusion experiments.