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. 2016 Mar 23;7(17):24348–24360. doi: 10.18632/oncotarget.8324

Figure 1. Effects of eIF5A2 on the invasion and metastasis of HCC cells.

Figure 1

(A) Representative phase-contrast images of wound closure of six HCC cell lines treated with GC7 (50 μM) or transfected with eIF5A2 siRNA (100 nM) at 0 and 48 h after creating the wound (magnification 100 ×). (B) Bar graphs based on quantitative data from (A). Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 versus control. (C) Representative photographs of invasion in the GC7 and eIF5A2 siRNA groups compared with the control groups in transwell assays (magnification 100 ×). (D) Graphs based on quantitative data from (C). Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 versus control. (E) Western hybridization confirming the effect of eIF5A2 siRNA transfection. (F) Bar graphs based on quantitative data from (E). Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001 versus control. Each experiment was repeated at least three times.