Table 4. PIK3CA mutational status according to liposarcoma histologic subtype.
| Histologic classification | Wild type | Mutation | |||||
|---|---|---|---|---|---|---|---|
| Exon 9 | Exon 20 | Total, n (%) | |||||
| E542K | E545K | Q546K | H1047R | H1047L | |||
| Well- and De-differentiated | 44 | 0 | 0 | 0 | 1 | 0 | 1 (2.2) |
| Well- differentiated | 1 | 0 | 1 | ||||
| De-differentiated | 0 | 0 | |||||
| Myxoid and Round cell, Pleomorphic | 52 | 2 | 1 | 2 | 2 | 1 | 8 (13.3) |
| Myxoid and Round cell | 43 | 2 | 0 | 1 | 2 | 1 | 6 |
| Pleomorphic | 9 | 0 | 1 | 1 | 0 | 0 | 2 |
| Total, n (%) | 96 (91.4) | 5 (4.8) | 4 (3.8) | P=0.043 | |||
| 9 (8.6) | |||||||