Skip to main content
. 2016 Mar 22;7(17):24734–24743. doi: 10.18632/oncotarget.8270

Figure 3. Identification of iGluR2/3 as direct targets of miR-124-3p using luciferase assays.

Figure 3

A-B. Schematic description of the hypothetical duplexes formed by interactions between miR-124-3p and the 3’UTR of iGluR2 (A) and iGluR3 (B). C-D. Direct recognition of iGluR2/3 through miR-124-3p (n=5). Firefly luciferase reporters containing either WT or mutant iGluR2 (C) and iGluR3 (D) 3’UTR sequences were co-transfected into HEK293T cells with scrambled non-coding RNA (NC) miRNA mimics, or miRNA inhibitors. At 24 h post-transfection, the cells were assayed using luciferase assay kits. ** indicates p<0.01.