Table 2. Incidence of thyroid cancer by sitagliptin exposure.
Sitagliptin use | Case number | Incident thyroid cancer | % | Person-years | Incidence rate |
---|---|---|---|---|---|
(per 100,000 person-years) | |||||
I. Original sample | |||||
Never users | 312853 | 172 | 0.05 | 777260.24 | 22.13 |
Ever users | 58238 | 28 | 0.05 | 95424.71 | 29.34 |
Tertiles of cumulative duration of sitagliptin therapy (months) | |||||
Never users | 312853 | 172 | 0.05 | 777260.24 | 22.13 |
<6.53 | 18287 | 9 | 0.05 | 25343.96 | 35.51 |
6.53-14.00 | 20161 | 14 | 0.07 | 29760.78 | 47.04 |
>14 | 19790 | 5 | 0.03 | 40319.97 | 12.40 |
II. Matched sample | |||||
Never users | 57659 | 31 | 0.05 | 141851.35 | 21.85 |
Ever users | 57659 | 28 | 0.05 | 94698.12 | 29.57 |
Tertiles of cumulative duration of sitagliptin therapy (months) | |||||
Never users | 57659 | 31 | 0.05 | 141851.35 | 21.85 |
<6.53 | 18066 | 9 | 0.05 | 25104.96 | 35.85 |
6.53-14.00 | 19978 | 14 | 0.07 | 29578.69 | 47.33 |
>14 | 19615 | 5 | 0.03 | 40014.47 | 12.50 |