Table 5. Hormonal features in the different GR polymorphic variant.

	N363S			Bcl1			ER22/23EK
	Wild type (n = 389)	Hetero-homozygote (n = 22)	p value	Wild type (n = 189)	Hetero-homozygote (n = 222)	p value	Wild type (n = 393)	Hetero-homozygote (n = 18)	p value
Cortisol post DST (mcg/dL)	2.4 ± 2.0	2.5 ± 1.7	0.8	2.5 ± 2.2	2.3 ± 1.9	0.3	2.4 ± 1.9	2.7 ± 2.6	0.5
ACTH (pg/mL)	14.5 ± 13.0	17.7 ± 12.1	0.3	16.3 ± 14.3	14.4 ± 8.1	0.09	14.2 ± 12.1	17.5 ± 14.7	0.3
UFC (% ULN, n.)	12.8 (50)	9.0 (2)	0.7	9.5 (18)	15.3 (34)	0.1	12.2 (48)	22.2 (4)	0.3

Data are expressed as mean ± SD with the exception of UFC expressed as percentage of patients with levels higher than the upper limit of normality (ULN) for the reference laboratory.

To convert conventional units to SI units: for cortisol, multiply by 27.59 to obtain nanomoles per liter; for ACTH, multiply by 0.22 to obtain picomoles per liter.