Table S2.
Bleeding pattern during the preceding 3 months before enrollment (baseline visit, efficacy population)
| Bleeding pattern parameters | Total (N=3,150)
|
E2 V/DNG (n=2,558)
|
POP (n=592)
|
|||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Regularity of withdrawal bleeding | ||||||
| Regular (once a month) | 2,680 | 85.1 | 2,177 | 85.1 | 503 | 85.0 |
| Occasionally absent | 426 | 13.5 | 351 | 13.7 | 75 | 12.7 |
| Amenorrhea | 38 | 1.2 | 25 | 1.0 | 13 | 2.2 |
| Maximum length of bleeding (days) | ||||||
| 1–2 | 302 | 9.7 | 239 | 9.5 | 63 | 10.9 |
| 3–5 | 2,055 | 66.2 | 1,653 | 65.4 | 402 | 69.6 |
| 6–7 | 615 | 19.8 | 523 | 20.7 | 92 | 15.9 |
| ≥8 | 126 | 4.1 | 107 | 4.2 | 19 | 3.3 |
| Maximum intensity of bleeding | ||||||
| Spotting | 205 | 6.6 | 164 | 6.5 | 41 | 7.1 |
| Light/scanty | 681 | 21.9 | 541 | 21.4 | 140 | 24.2 |
| Normal | 1,703 | 54.8 | 1,397 | 55.3 | 306 | 52.9 |
| Heavy | 500 | 16.1 | 411 | 16.3 | 89 | 15.4 |
| Painful bleeding | ||||||
| Yes | 2,265 | 71.9 | 1,823 | 71.3 | 442 | 74.7 |
| No | 864 | 27.4 | 720 | 28.1 | 144 | 24.3 |
| Intracyclic bleeding (more than once a month) | ||||||
| Yes | 2,676 | 85.0 | 2,157 | 84.3 | 519 | 87.7 |
| No | 454 | 14.4 | 386 | 15.1 | 68 | 11.5 |
Abbreviations: E2V/DNG, estradiol valerate and dienogest; POP, progestogen-only pill.