Table 2. MRI and clinical indices mean changes (95% CI) from baseline from analysis of variance.
| 3 months | 6 months | 12 months | |
|---|---|---|---|
| CENTRAL SLICE TOTAL MUSCLE COMPARTMENT FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 1.4 | 3.9 | 5.0 |
| (-0.3, 3.2) | (1.9, 5.7) | (3.2, 6.9) | |
| No. of subjects | 9 | 7 | 7 |
| P value | 0.11 | < 0.001 | < 0.001 |
| PROXIMAL SLICE TOTAL MUSCLE COMPARTMENT FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 2.1 | 4.5 | 6.9 |
| (0.5, 3.7) | (2.7, 6.3) | (5.2, 8.7) | |
| No. of subjects | 9 | 7 | 7 |
| P value | 0.01 | < 0.001 | < 0.001 |
| DISTAL SLICE TOTAL MUSCLE COMPARTMENT FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 2.2 | 2.2 | 4.3 |
| (0.06, 4.3) | (-0.05, 4.5) | (2.0, 6.6) | |
| No. of subjects | 9 | 7 | 7 |
| P value | 0.04 | 0.06 | < 0.001 |
| CENTRAL SLICE DORSAL COMPARTMENT FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 1.7 | 5.5 | 6.3 |
| (-0.9, 4.4) | (2.7, 8.3) | (3.6, 9.1) | |
| No. of subjects | 9 | 7 | 8 |
| P value | 0.20 | <0.001 | <0.001 |
| CENTRAL SLICE VOLAR COMPARTMENT FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 1.3 | 0.7 | 3.4 |
| (-1.0, 3.7) | (-1.8, 3.3) | (0.9, 5.7) | |
| No. of subjects | 9 | 7 | 8 |
| P value | 0.27 | 0.58 | <0.01 |
| ECRLB Br FAT FRACTION (%) | |||
| Mean change from baseline (95% CI) | 1.7 | 6.1 | 7.0 |
| (-1.1, 4.5) | (3.1, 9.2) | (4.1, 10.0) | |
| No. of subjects | 9 | 7 | 8 |
| P value | 0.24 | <0.001 | <0.001 |
| CENTRAL SLICE TOTAL MUSCLE COMPARTMENT CROSS-SECTIONAL MUSCLE AREA (mm2) | |||
| Mean change from baseline (95% CI) | -5.4 | 42.1 | 140 |
| (-88.1, 77.4) | (-47.0, 131.2) | (50.9, 229.1) | |
| No. of subjects | 9 | 7 | 7 |
| P value | 0.90 | 0.36 | < 0.01 |
| CENTRAL SLICE TOTAL REMAINING (NON-FAT) MUSCLE AREA (mm2) | |||
| Mean change from baseline (95% CI) | -28.4 | -32.1 | 22.0 |
| (-93.6, 36.8) | (-102.6, 38.1) | (-48.2, 92.3) | |
| No. of subjects | 9 | 7 | 7 |
| P value | 0.39 | 0.37 | 0.54 |
| MYOPINCH (Kg) | |||
| Mean change from baseline (95% CI) | -0.1 | -0.38 | -0.50 |
| (-0.27, 0.03) | (-0.53, -0.22) | (-0.66, -0.34) | |
| No. of subjects | 10 | 9 | 8 |
| P value | 0.12 | < 0.001 | < 0.001 |
| MYOGRIP (Kg) | |||
| Mean change from baseline (95% CI) | -0.22 | -0.50 | -1.04 |
| (-0.70, 0.27) | (-1.01, 0.002) | (-1.56, -0.51) | |
| No. of subjects | 10 | 9 | 8 |
| P value | 0.38 | 0.05 | < 0.001 |
| PERFORMANCE OF UPPER LIMB (Total score = 74) | |||
| Mean change from baseline (95% CI) | -0.5 | -2.6 | -9.2 |
| (-2.8, 1.9) | (-5.2, -0.03) | (-11.9, -6.4) | |
| No. of subjects | 14 | 11 | 9 |
| P value | 0.69 | 0.05 | < 0.001 |
| PERFORMANCE OF UPPER LIMB (Shoulder domain score = 16) | |||
| Mean change from baseline (95% CI) | -0.7 | -1.0 | -6.9 |
| (-2.6, 1.1) | (-2.9, 0.9) | (-9.0, -4.9) | |
| No. of subjects | 14 | 11 | 9 |
| P value | 0.42 | 0.32 | < 0.001 |
| MOVIPLATE (taps in 30 seconds) | |||
| Mean change from baseline (95% CI) | 2.3 | 4.7 | 1.7 |
| (-0.02, 4.6) | (2.01, 7.4) | (-0.8, 4.3) | |
| No. of subjects | 11 | 9 | 8 |
| P value | 0.05 | 0.001 | 0.19 |
P value < 0.01 was considered significant. ECRLB Br = extensor carpi radialis longus/brevis and brachioradialis