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. 2016 Sep 20;11(9):e0163257. doi: 10.1371/journal.pone.0163257

Table 1. Characteristics of included studies.

Author Year Country Age(y) Case Control Method Case type Control type
M U M U
Bammidi LS 2012 India 20–75 28 22 18 32 BSP tissues blood
Bhagat R 2014 India 20–79 58 76 11 30 MSP tissues tissues
Li M 2006 China NA 6 12 0 10 MSP tissues tissues
Liu Z 2005 USA 27–81 13 39 15 25 MSP tissues tissues
Makarla P 2005 USA 51.5(20–86) 7 16 3 36 MSP tissues tissues
Niederacher D 1999 Germany NA 6 17 0 10 MSP tissues tissues
Shih YC 1997 Australia NA 0 45 0 2 MSP tissues tissues
Tam KF 2007 China 53.1±1.4 17 72 5 30 MSP tissues tissues
Wong YF 1999 China NA 2 47 0 10 MSP tissues blood
Shen W 2008 China 52.2, 53.2 13 50 0 30 BSP tissues tissues
Wei W 1999 China 46.5±12.47 5 21 0 2 BSP tissues tissues
Xu B 2003 China NA 4 36 0 20 MSP tissues tissues

Blood: peripheral blood samples from each patient with ovarian cancer; tissues: benign ovarian tissues, normal ovarian tissues of cancer-free patients and adjacent tissues; MSP: methylation-specific polymerase chain reaction; BSP: bisulfite sequencing PCR; NA: not available; M: methylation; U: unmethylation.