Table 2. Tropomyosin isoform expression in normal controls and patients with Type 2 diabetes.
| Gene | Isoform | Group | Mean (95% CI) | P Value |
|---|---|---|---|---|
| TPM1 | HMW | Normal | 1.00 (0.63–1.59) | |
| Diabetic | 0.55 (0.42–0.72) | 0.019 | ||
| LMW | Normal | 1.00 (0.75–1.33) | ||
| Diabetic | 0.94 (0.82–1.07) | 0.656 | ||
| TPM4 | HMW | Normal | 1.00 (0.71–1.42) | |
| Diabetic | 0.76 (0.58–0.99) | 0.205 | ||
| LMW | Normal | 1.00 (0.80–1.24) | ||
| Diabetic | 0.81 (0.68–0.97) | 0.140 |
Relative mean (and 95% confidence interval) mRNA expression of high and low molecular weight tropomyosin isoforms in normal control individuals and patients with Type 2 diabetes.