Table 3. TPM1 and TPM4 expression in response to glucose and insulin.
| Gene | Isoform | Treatment | Mean (95% CI) | P Value (to LILG) |
|---|---|---|---|---|
| TPM1 | HMW | LILG | 1.00 (0.95–1.05) | |
| HILG | 0.95 (0.92–0.98) | 0.27 | ||
| LIHG | 0.97 (0.92–1.02) | 0.73 | ||
| HIHG | 1.10 (1.05–1.15) | 0.01 | ||
| LMW | LILG | 1.00 (0.97–1.03) | ||
| HILG | 1.00 (0.98–1.03) | 1.00 | ||
| LIHG | 1.01 (0.97–1.05) | 0.97 | ||
| HIHG | 1.03 (1–1.07) | 0.43 | ||
| TPM4 | HMW | LILG | 1.00 (0.9–1.11) | |
| HILG | 1.07 (0.99–1.16) | 0.61 | ||
| LIHG | 1.01 (0.95–1.08) | 1.00 | ||
| HIHG | 1.15 (1.06–1.26) | 0.07 | ||
| LMW | LILG | 1.00 (0.96–1.04) | ||
| HILG | 1.05 (1.02–1.08) | 0.08 | ||
| LIHG | 1.07 (1.04–1.1) | 0.01 | ||
| HIHG | 1.07 (1.04–1.1) | 0.01 |
Mean tropomyosin isoform expression in THP1 cells in response to elevated concentrations of glucose and insulin.