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. 2016 Sep 7;38(4):1199–1207. doi: 10.3892/ijmm.2016.2730

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Tumor transplantation assay using BALB/c-nu/nu mice. (A) The body weights of the mice injected with NaCl, or the CD133⁻CD44⁻ cells or CD133⁺CD44⁺ cells were measured over a period of 4 weeks. (B) Tumors of the mice in the CD133⁺CD44⁺ group injected with various concentrations of the cells (B1, 200,000 cells; B2, 20,000 cells; B3, 2,000 cells) were measured using a ruler (cm). (C) Tumor growth curves of the mice injected with various concentrations of CD133⁺CD44⁺ cells (200,000, 20,000 or 2,000 cells); ^*P<0.05. (D) Pathological section examination stained with hematoxylin and eosin (H&E) under a microscope (×400 magnification).

Tumor transplantation assay using BALB/c-nu/nu mice. (A) The body weights of the mice injected with NaCl, or the CD133⁻CD44⁻ cells or CD133⁺CD44⁺ cells were measured over a period of 4 weeks. (B) Tumors of the mice in the CD133⁺CD44⁺ group injected with various concentrations of the cells (B1, 200,000 cells; B2, 20,000 cells; B3, 2,000 cells) were measured using a ruler (cm). (C) Tumor growth curves of the mice injected with various concentrations of CD133⁺CD44⁺ cells (200,000, 20,000 or 2,000 cells); ^*P<0.05. (D) Pathological section examination stained with hematoxylin and eosin (H&E) under a microscope (×400 magnification).