Table I.

Statistical results and chromosomal locations of miRNAs in HPrAD-vis cells treated with 5 mM metformin for 1 week compared to control cells (P<0.05).

Name	Fold-change (treated/control)	SD	P-value	Location
miR-664a-5p	2.57	0.406	0.0090	1
miR-3687a	2.34	0.910	0.0229	21
miR-4664-3p	2.30	0.904	0.0153	8
miR-1246a	1.78	0.363	0.0107	2
miR-4783-3p	1.74	0.183	0.0010	2
miR-4656	1.58	0.266	0.0019	7
miR-1539	0.64	0.362	0.0136	18
miR-148b-3pa	0.64	0.198	0.0109	12
miR-4638-3p	0.63	0.165	0.0170	5
miR-515-5p	0.62	0.325	0.0205	19
miR-134	0.61	0.273	0.0313	14
miR-939-5p	0.60	0.239	0.0360	8
miR-378a-3pa	0.54	0.069	0.0004	5
miR-378ia	0.49	0.090	0.0115	22
miR-422aa	0.45	0.066	0.0068	15
miR-425-3p	0.42	0.185	0.0420	3
miR-661	0.42	0.307	0.0244	8
miR-615-5p	0.40	0.233	0.0481	12
miR-3160-3p	0.21	0.019	0.0037	11

^amiRNAs were matched to miRNAs extracted from cells treated with 5 mM metformin for 2 weeks as shown in Table II. miRNAs, microRNAs; HPrAD-vis, human visceral preadipocytes; SD, standard deviation.