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. Author manuscript; available in PMC: 2017 May 25.
Published in final edited form as: J Am Chem Soc. 2016 May 11;138(20):6372–6375. doi: 10.1021/jacs.6b02653

Table 3.

Tandem Cross Metathesis/Oxidative Cyclization of 1,5-Dienes with Terminal Olefins

graphic file with name nihms-813235-f0014.jpg
Entry 5 4 Product 6 Yield (%)a
l 5a 4a graphic file with name nihms-813235-t0015.jpg 6a 65
2 5a 4b graphic file with name nihms-813235-t0016.jpg 6b 66
3 5a 4c graphic file with name nihms-813235-t0017.jpg 6c 60
4 5a 4d graphic file with name nihms-813235-t0018.jpg 6d 59b
5 5b 4a graphic file with name nihms-813235-t0019.jpg 6e 69
6 5b 4b graphic file with name nihms-813235-t0020.jpg 6f 73
7 5c 4b graphic file with name nihms-813235-t0021.jpg 6g 73
8 5d 4b graphic file with name nihms-813235-t0022.jpg 6h 60
9 5e 4b graphic file with name nihms-813235-t0023.jpg 6i 42
10 5f 4a graphic file with name nihms-813235-t0024.jpg 6j 76
11 5f 4b graphic file with name nihms-813235-t0025.jpg 6k 63
a

Isolated as a single diastereomer.

b

1.25 of equiv of 4d, 5 mol % Ru-4; see Supporting Information for details.